6sense’s AI Email Agents combine the company’s vast B2B dataset (the Signalverse) with generative AI to run email outreach campaigns autonomously. The system uses “out-of-the-box” playbooks to craft AI-generated, 1:1 email sequences tailored to each prospect, drawing on intent signals, firmographics, CRM/MAP fields and your content to personalize every message. It automatically sends follow-ups and even books meetings when recipients engage. Built-in deliverability infrastructure (inbox warming, domain management, and contact validation) ensures high inbox placement. In short, it lets sales teams leverage data-driven email campaigns (both outbound and inbound qualification) with minimal manual effort.

• Free tier: 50 credits/month (basic Buyer Discovery, contact/company lookup, alerts).
• Paid: Team / Growth / Enterprise - quote-based, bundled features; costs scale with account size/credits.
• Subscription model + credits; buyers report typical annual spend in the tens - hundreds of thousands.

• AI-generated 1:1 email writer
• Out-of-the-box playbooks for sequenced campaigns and multi-touch drip flows.
• Reply detection/classification
• Context-aware follow-ups.
• Lead routing into CRM tasks and continuous A/B testing of subject/content.
• Content library & playbook management.

• Email

• Integration-heavy - connects to Salesforce/HubSpot/Marketo/Pardot and requires configuring intent/playbooks.
• Steep learning curve; often requires CSM/professional services.
• Typical deployment: weeks to months (CRM cleanup, ICPs, testing).

• Domain management
• Automated inbox warming
• SPF/DKIM/DMARC setup
• Health monitoring.
• Contact validation / email hygiene and send-rate throttling
• Dedicated IPs available for enterprise
• Deliverability dashboards to monitor opens/bounces
• Leverages large verified email database

• Tweakable playbooks
• Sequence cadence
• Targeting rules
• Campaign goals
• Merge any combination of CRM/MAP fields
• 6sense signals for deep personalization
• Human-in-loop options for review/approval

• Relies on 6sense “Signalverse” (large proprietary B2B signal dataset)
• Uses first and third-party intent signals
• Ongoing data refresh from crawlers/partners
• Format checks
• Duplicate suppression
• Segmentation by intent/fit

• True account-level and contact-level personalization (industry, tech stack, intent topics, etc).
• ML optimizes copy and personalization over time
• Dynamic A/B testing based on opens/replies.
• Marketers can audit drafts/analytics to keep tone/compliance human-friendly

• Co-Pilot mode
• Fully automatic
• Manual

• Native syncs (Salesforce, HubSpot, etc.)
• MAP integrations (Marketo, Pardot)
• Calendar/email provider support (Gmail/Office365)
• APIs
• Webhooks

• Possibly a dedicated CSM for onboarding, training, docs and webinars
• Active user community
• Enterprise customers get higher-touch support
• Some reports of slower support post-launch

6sense AI Email Agents are best suited for mid-market to enterprise B2B companies with established account-based strategies. It works well when you have: multiple stakeholders per deal, longer sales cycles, and a need to scale personalized outbound email. Teams in technology, business services or other complex B2B sectors use it to turbocharge both outbound campaigns and inbound lead follow-up. It is not designed for very small startups or one-person sales shops (where simpler tools are preferred).